impact

Launched in September 2025, the “Defying Osteosarcoma” project led by Break Through Cancer is the largest-ever investment in osteosarcoma research. This $15 million project is supported by patient-driven foundations including Battle Osteosarcoma as a lead funder. The Defying Osteosarcoma TeamLab mobilizes the largest, most unified effort in pediatric osteosarcoma research in North America designed to dismantle the barriers that have historically slowed progress in this disease: inadequate data sharing, siloed infrastructure, and absence of unified investment. By aligning institutions, data, and funding under a single collaborative framework, Break Through Cancer’s Defying Osteosarcoma TeamLab brings together more than 20 researchers from eight institutions: Dana-Farber Cancer Institute, Memorial Sloan Kettering Cancer Center, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The University of Texas MD Anderson Cancer Center, BC Cancer Research Institute, Cummings School of Veterinary Medicine at Tufts University, Stanford Medicine, and The UCSF Helen Diller Family Comprehensive Cancer Center. This coordinated, multi-year effort plans to rewrite the future of osteosarcoma care. Patients and families facing osteosarcoma deserve more than incremental progress; they deserve an ambitious plan that unites the best minds, the best institutions, and the most determined advocates. Battle Osteosarcoma is proud to support this unprecedented research project for osteosarcoma. Learn more about this incredible project HERE.